Endocrine Abstracts

Mesenchymal stem cell (MSC), as a significant part of regenerative medicine, has been considered as a promising therapy in several diseases. Recently, the secretion effect of MSCs has been found to play a key role in the regulation of inflammatory. Here, we screened different peptides with high expression abundance by mass spectrometry from the supernatant of human umbilical cord MSCs. Also, we identified a peptide (AQTKRLVGDVLLATAFLSYSGP) named MSC-P2 derived from dynein axon...

Obesity, as a chronic nutritional disorder, is a high-risk factor for type 2 diabetes, fatty liver and other metabolic diseases. Multiple lncRNAs have been confirmed concerning adipocyte differentiation and thus affect obesity, such as ADINR, Paral1, etc. Previously, we identified a lncRNA named ENST0000052114 (abbreviated to lncRNA52114), highly expressed in human mature adipocytes by differential lncRNA expression profile. Here, we explored the role and mechanism of lncRNA52...